T51I (p.Thr51Ile) variant of MS4A1 (B-lymphocyte antigen CD20)
T51I (p.Thr51Ile) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T51I (p.Thr51Ile) variant details
- p.Thr51Ile
- TOPMed rs1210984901
- gnomAD rs1210984901
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.01
- MetaLR 0.01
- MetaSVM -0.94
- CADD 15.10
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available