T51A (p.Thr51Ala) variant of MS4A1 (B-lymphocyte antigen CD20)
T51A (p.Thr51Ala) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
T51A (p.Thr51Ala) variant details
- p.Thr51Ala
- gnomAD rs2086256652
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.01
- MetaLR 0.00
- MetaSVM -0.92
- CADD 11.50
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available