T41R (p.Thr41Arg) variant of MS4A1 (B-lymphocyte antigen CD20)
T41R (p.Thr41Arg) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
T41R (p.Thr41Arg) variant details
- p.Thr41Arg
- gnomAD 11-60462496-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.12
- CADD 22.70
- PolyPhen-2 0.88
- SIFT 0.01
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available