T3I (p.Thr3Ile) variant of MS4A1 (B-lymphocyte antigen CD20)
T3I (p.Thr3Ile) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T3I (p.Thr3Ile) variant details
- p.Thr3Ile
- gnomAD rs1208417279
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.14
- MetaLR 0.14
- MetaSVM -1.01
- CADD 25.00
- PolyPhen-2 0.64
- SIFT 0.04
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available