R33G (p.Arg33Gly) variant of MS4A1 (B-lymphocyte antigen CD20)
R33G (p.Arg33Gly) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R33G (p.Arg33Gly) variant details
- p.Arg33Gly
- TOPMed rs1222925482
- gnomAD rs1222925482
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.14
- MetaLR 0.07
- MetaSVM -1.06
- CADD 19.80
- PolyPhen-2 0.24
- SIFT 0.42
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available