R32G (p.Arg32Gly) variant of MS4A1 (B-lymphocyte antigen CD20)
R32G (p.Arg32Gly) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
R32G (p.Arg32Gly) variant details
- p.Arg32Gly
- gnomAD 11-60462468-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.10
- CADD 7.61
- PolyPhen-2 0.17
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available