P4T (p.Pro4Thr) variant of MS4A1 (B-lymphocyte antigen CD20)
P4T (p.Pro4Thr) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
P4T (p.Pro4Thr) variant details
- p.Pro4Thr
- gnomAD 11-60462384-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.18
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available
- Literature evidence available