P20S (p.Pro20Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
P20S (p.Pro20Ser) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P20S (p.Pro20Ser) variant details
- p.Pro20Ser
- Ensembl rs2135197220
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.04
- MetaLR 0.09
- MetaSVM -1.05
- CADD 15.10
- PolyPhen-2 0.73
- SIFT 0.35
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available