P16S (p.Pro16Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
P16S (p.Pro16Ser) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
P16S (p.Pro16Ser) variant details
- p.Pro16Ser
- Ensembl rs2135197187
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.09
- MetaLR 0.04
- MetaSVM -1.07
- CADD 10.30
- PolyPhen-2 0.01
- SIFT 0.38
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available