N6S (p.Asn6Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
N6S (p.Asn6Ser) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
N6S (p.Asn6Ser) variant details
- p.Asn6Ser
- gnomAD rs1483638139
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.08
- CADD 22.80
- PolyPhen-2 0.68
- SIFT 0.10
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available