M46V (p.Met46Val) variant of MS4A1 (B-lymphocyte antigen CD20)
M46V (p.Met46Val) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
M46V (p.Met46Val) variant details
- p.Met46Val
- TOPMed rs1221258124
- gnomAD rs1221258124
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.07
- CADD 11.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available