M46R (p.Met46Arg) variant of MS4A1 (B-lymphocyte antigen CD20)
M46R (p.Met46Arg) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
M46R (p.Met46Arg) variant details
- p.Met46Arg
- gnomAD 11-60462511-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.03
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- Literature evidence available