M34L (p.Met34Leu) variant of MS4A1 (B-lymphocyte antigen CD20)
M34L (p.Met34Leu) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data, published literature, and structural context.
M34L (p.Met34Leu) variant details
- p.Met34Leu
- gnomAD 11-60462474-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0337
- REVEL 0.01
- CADD 0.44
- PolyPhen-2 0.00
- SIFT 0.67
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available
- Literature evidence available