M34K (p.Met34Lys) variant of MS4A1 (B-lymphocyte antigen CD20)
M34K (p.Met34Lys) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
M34K (p.Met34Lys) variant details
- p.Met34Lys
- ExAC rs776822308
- gnomAD rs776822308
- Missense
- Variant Prioritization Score for Impact Estimate 0.0865
- REVEL 0.04
- MetaLR 0.04
- MetaSVM -1.03
- CADD 2.87
- PolyPhen-2 0.02
- SIFT 0.72
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available