L61F (p.Leu61Phe) variant of MS4A1 (B-lymphocyte antigen CD20)
L61F (p.Leu61Phe) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L61F (p.Leu61Phe) variant details
- p.Leu61Phe
- TOPMed rs2086261115
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.23
- MetaLR 0.02
- MetaSVM -1.04
- CADD 19.30
- PolyPhen-2 0.21
- SIFT 0.04
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available