L52S (p.Leu52Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
L52S (p.Leu52Ser) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L52S (p.Leu52Ser) variant details
- p.Leu52Ser
- Ensembl rs1565194218
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.31
- MetaLR 0.10
- MetaSVM -0.75
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available