K28T (p.Lys28Thr) variant of MS4A1 (B-lymphocyte antigen CD20)
K28T (p.Lys28Thr) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
K28T (p.Lys28Thr) variant details
- p.Lys28Thr
- gnomAD 11-60462457-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.08
- CADD 13.60
- PolyPhen-2 0.52
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- Literature evidence available