K28* (p.Lys28Ter) variant of MS4A1 (B-lymphocyte antigen CD20)
K28* (p.Lys28Ter) in MS4A1 (B-lymphocyte antigen CD20) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
K28* (p.Lys28Ter) variant details
- p.Lys28Ter
- ExAC rs780340225
- gnomAD rs780340225
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.52
- CADD 32.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available