H63Q (p.His63Gln) variant of MS4A1 (B-lymphocyte antigen CD20)
H63Q (p.His63Gln) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
H63Q (p.His63Gln) variant details
- p.His63Gln
- gnomAD 11-60463031-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.27
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available