G60R (p.Gly60Arg) variant of MS4A1 (B-lymphocyte antigen CD20)
G60R (p.Gly60Arg) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
G60R (p.Gly60Arg) variant details
- p.Gly60Arg
- gnomAD 11-60463020-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.637
- REVEL 0.51
- CADD 29.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available