G60E (p.Gly60Glu) variant of MS4A1 (B-lymphocyte antigen CD20)
G60E (p.Gly60Glu) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
G60E (p.Gly60Glu) variant details
- p.Gly60Glu
- gnomAD 11-60463021-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.48
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available