G39D (p.Gly39Asp) variant of MS4A1 (B-lymphocyte antigen CD20)
G39D (p.Gly39Asp) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G39D (p.Gly39Asp) variant details
- p.Gly39Asp
- Ensembl rs2135197374
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.21
- MetaLR 0.11
- MetaSVM -1.05
- CADD 24.00
- PolyPhen-2 0.97
- SIFT 0.08
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available