G26S (p.Gly26Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
G26S (p.Gly26Ser) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G26S (p.Gly26Ser) variant details
- p.Gly26Ser
- Ensembl rs2135197266
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -1.04
- CADD 3.97
- PolyPhen-2 0.01
- SIFT 0.68
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available