G10E (p.Gly10Glu) variant of MS4A1 (B-lymphocyte antigen CD20)
G10E (p.Gly10Glu) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G10E (p.Gly10Glu) variant details
- p.Gly10Glu
- Ensembl rs2135197141
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.22
- MetaLR 0.28
- MetaSVM -0.85
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available