A54S (p.Ala54Ser) variant of MS4A1 (B-lymphocyte antigen CD20)
A54S (p.Ala54Ser) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
A54S (p.Ala54Ser) variant details
- p.Ala54Ser
- gnomAD 11-60463002-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.26
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available