A22T (p.Ala22Thr) variant of MS4A1 (B-lymphocyte antigen CD20)
A22T (p.Ala22Thr) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A22T (p.Ala22Thr) variant details
- p.Ala22Thr
- ExAC rs779510338
- gnomAD rs779510338
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.01
- MetaLR 0.04
- MetaSVM -1.02
- CADD 4.71
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available