A22A (p.Ala22Ala) variant of MS4A1 (B-lymphocyte antigen CD20)
A22A (p.Ala22Ala) in MS4A1 (B-lymphocyte antigen CD20) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
A22A (p.Ala22Ala) variant details
- p.Ala22Ala
- rs1343328268
- gnomAD 11-60462440-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.41
- CADD 5.19
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available