A14G (p.Ala14Gly) variant of MS4A1 (B-lymphocyte antigen CD20)
A14G (p.Ala14Gly) in MS4A1 (B-lymphocyte antigen CD20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A14G (p.Ala14Gly) variant details
- p.Ala14Gly
- cosmic curated COSV61942
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.10
- MetaLR 0.04
- MetaSVM -1.05
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available