W68C (p.Trp68Cys) variant of MOG (Q16653)
W68C (p.Trp68Cys) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
W68C (p.Trp68Cys) variant details
- p.Trp68Cys
- gnomAD 6-29659434-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.852
- REVEL 0.89
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available