S5* (p.Ser5Ter) variant of MOG (Q16653)
S5* (p.Ser5Ter) in MOG (Q16653) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S5* (p.Ser5Ter) variant details
- p.Ser5Ter
- NCI-TCGA TCGA novel
- ExAC rs762765531
- TOPMed rs762765531
- gnomAD rs762765531
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.261
- CADD 25.40
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available