S3R (p.Ser3Arg) variant of MOG (Q16653)
S3R (p.Ser3Arg) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
S3R (p.Ser3Arg) variant details
- p.Ser3Arg
- gnomAD 6-29657216-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0794
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -1.03
- CADD 2.50
- PolyPhen-2 0.02
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available