P7L (p.Pro7Leu) variant of MOG (Q16653)
P7L (p.Pro7Leu) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P7L (p.Pro7Leu) variant details
- p.Pro7Leu
- ExAC rs774294291
- gnomAD rs774294291
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -0.99
- CADD 9.29
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the African/African-American population (allele frequency 0.00015)
- Structural context available