P57T (p.Pro57Thr) variant of MOG (Q16653)
P57T (p.Pro57Thr) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
P57T (p.Pro57Thr) variant details
- p.Pro57Thr
- gnomAD 6-29659399-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.495
- REVEL 0.31
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available