M64L (p.Met64Leu) variant of MOG (Q16653)
M64L (p.Met64Leu) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
M64L (p.Met64Leu) variant details
- p.Met64Leu
- gnomAD 6-29659420-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.18
- CADD 24.40
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available