L20I (p.Leu20Ile) variant of MOG (Q16653)
L20I (p.Leu20Ile) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
L20I (p.Leu20Ile) variant details
- p.Leu20Ile
- TOPMed rs1767296639
- Missense
- Variant Prioritization Score for Impact Estimate 0.0839
- REVEL 0.02
- MetaLR 0.03
- MetaSVM -1.07
- CADD 3.77
- PolyPhen-2 0.02
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available