L20F (p.Leu20Phe) variant of MOG (Q16653)
L20F (p.Leu20Phe) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
L20F (p.Leu20Phe) variant details
- p.Leu20Phe
- gnomAD 6-29657267-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0993
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -1.01
- CADD 4.27
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available