L19F (p.Leu19Phe) variant of MOG (Q16653)
L19F (p.Leu19Phe) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L19F (p.Leu19Phe) variant details
- p.Leu19Phe
- TOPMed rs909239151
- gnomAD rs909239151
- Missense
- Variant Prioritization Score for Impact Estimate 0.0999
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -0.99
- CADD 2.11
- PolyPhen-2 0.25
- SIFT 0.46
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available