L18P (p.Leu18Pro) variant of MOG (Q16653)
L18P (p.Leu18Pro) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L18P (p.Leu18Pro) variant details
- p.Leu18Pro
- ESP rs150396974
- TOPMed rs150396974
- gnomAD rs150396974
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.27
- MetaLR 0.07
- MetaSVM -1.01
- CADD 22.90
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available