L17V (p.Leu17Val) variant of MOG (Q16653)
L17V (p.Leu17Val) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
L17V (p.Leu17Val) variant details
- p.Leu17Val
- gnomAD 6-29657258-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0958
- REVEL 0.01
- MetaLR 0.02
- MetaSVM -1.05
- CADD 1.64
- PolyPhen-2 0.01
- SIFT 0.85
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available