L17F (p.Leu17Phe) variant of MOG (Q16653)
L17F (p.Leu17Phe) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L17F (p.Leu17Phe) variant details
- p.Leu17Phe
- ExAC rs761254394
- gnomAD rs761254394
- Missense
- Variant Prioritization Score for Impact Estimate 0.0979
- REVEL 0.01
- MetaLR 0.02
- MetaSVM -0.98
- CADD 3.60
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the East Asian population (allele frequency 3.2e-05)
- Structural context available