K59R (p.Lys59Arg) variant of MOG (Q16653)
K59R (p.Lys59Arg) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
K59R (p.Lys59Arg) variant details
- p.Lys59Arg
- gnomAD 6-29659406-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.02
- CADD 15.70
- PolyPhen-2 0.04
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available