I41L (p.Ile41Leu) variant of MOG (Q16653)
I41L (p.Ile41Leu) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
I41L (p.Ile41Leu) variant details
- p.Ile41Leu
- TOPMed rs1489289337
- gnomAD rs1489289337
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.08
- CADD 13.60
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available