I35T (p.Ile35Thr) variant of MOG (Q16653)
I35T (p.Ile35Thr) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I35T (p.Ile35Thr) variant details
- p.Ile35Thr
- ExAC rs771221017
- TOPMed rs771221017
- gnomAD rs771221017
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.18
- CADD 20.30
- PolyPhen-2 0.04
- SIFT 0.63
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available