H39Q (p.His39Gln) variant of MOG (Q16653)
H39Q (p.His39Gln) in MOG (Q16653) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.03 / 1. The record also includes population frequency data and structural context.
H39Q (p.His39Gln) variant details
- p.His39Gln
- NCI-TCGA Cosmic COSV1009
- cosmic curated COSV10097
- TOPMed rs1767946826
- gnomAD rs1767946826
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0326
- REVEL 0.02
- CADD 0.04
- PolyPhen-2 0.01
- SIFT 0.20
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available