G46R (p.Gly46Arg) variant of MOG (Q16653)
G46R (p.Gly46Arg) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
G46R (p.Gly46Arg) variant details
- p.Gly46Arg
- 1000Genomes rs368958442
- ESP rs368958442
- ExAC rs368958442
- TOPMed rs368958442
- Missense
- Variant Prioritization Score for Impact Estimate 0.708
- REVEL 0.75
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the 1KG:ITU population (allele frequency 0.0049)
- Structural context available