C14W (p.Cys14Trp) variant of MOG (Q16653)
C14W (p.Cys14Trp) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
C14W (p.Cys14Trp) variant details
- p.Cys14Trp
- gnomAD 6-29657251-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.03
- MetaLR 0.01
- MetaSVM -1.02
- CADD 7.59
- PolyPhen-2 0.01
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available