A2T (p.Ala2Thr) variant of MOG (Q16653)
A2T (p.Ala2Thr) in MOG (Q16653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- gnomAD rs1390934933
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.05
- MetaLR 0.02
- MetaSVM -1.01
- CADD 14.50
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available