R21W (p.Arg21Trp) variant of MET (P08581)
R21W (p.Arg21Trp) in MET (P08581) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R21W (p.Arg21Trp) variant details
- p.Arg21Trp
- Ensembl rs2116579265
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.14
- AlphaMissense 0.12
- MetaLR 0.32
- MetaSVM -0.53
- CADD 24.50
- PolyPhen-2 0.93
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available