L18L (p.Leu18Leu) variant of MET (P08581)
L18L (p.Leu18Leu) in MET (P08581) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L18L (p.Leu18Leu) variant details
- p.Leu18Leu
- rs1260001540
- gnomAD 7-116699136-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.35
- AlphaMissense 0.08
- MetaLR 0.47
- MetaSVM 0.00
- CADD 10.40
- PolyPhen-2 0.54
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available