L12L (p.Leu12Leu) variant of MET (P08581)
L12L (p.Leu12Leu) in MET (P08581) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
L12L (p.Leu12Leu) variant details
- p.Leu12Leu
- rs188625702
- gnomAD 7-116699120-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0914
- CADD 1.52
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available
- Literature evidence available